Non-HDL Cholesterol Target Tracker (NICE NG238)

Enter baseline and current non-HDL cholesterol. See the percentage reduction and whether NICE targets are met.

By Dr Amer Sheikh, GP Updated 17 October 2026 Clinical review pending

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NICE lipid targets

Setting	Target (NICE NG238)
Primary prevention	More than 40% reduction in non-HDL cholesterol from baseline
Secondary prevention	LDL 2.0 mmol/L or less, or non-HDL 2.6 mmol/L or less

If the target is not met

Check adherence and side effects first.
Increase statin intensity, for example atorvastatin 80 mg.
Then consider adding ezetimibe.
Recheck lipids 2 to 3 months after a change.

Frequently asked questions

What is the NICE target for non-HDL cholesterol?

A reduction of more than 40% from baseline on a statin.

What is the secondary prevention lipid target?

LDL 2.0 mmol/L or less, or non-HDL 2.6 mmol/L or less.

When should lipids be rechecked?

Around 3 months after starting or changing a statin.

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References

NICE. Cardiovascular disease: risk assessment and reduction, including lipid modification (2023). NG238. nice.org.uk/guidance/ng238

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