Estimate the likelihood of familial hypercholesterolaemia (FH) with the DLCN criteria.
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It combines family history, personal history, examination, LDL cholesterol and DNA results to estimate the chance of FH.
| Score | Result |
|---|---|
| Below 3 | FH unlikely |
| 3–5 | Possible FH |
| 6–8 | Probable FH |
| Over 8 | Definite FH |
NICE advises referral to a specialist lipid clinic for DNA testing when the score is over 5.
Suspect FH with total cholesterol over 7.5 mmol/L and a family history of premature heart disease.
A score over 5 (probable or definite FH).
The Simon Broome criteria. NICE accepts either.
Yes. Cascade testing of relatives is key once FH is confirmed.
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