When to adjust the dose
- Body weight under 50 kg
- Chronic alcohol excess
- Malnutrition
- Hepatic impairment
- Enzyme-inducing drugs
Dosing
Consider 15 mg/kg per dose, every 4 to 6 hours, up to 4 doses in 24 hours. Standard adult dosing is 1 g up to four times daily, maximum 4 g.
Frequently asked questions
What is the paracetamol dose for someone under 50 kg?
Consider 15 mg/kg per dose, up to four times a day.
Why reduce paracetamol in low weight?
To reduce the risk of liver toxicity.
What if the dose falls between tablet sizes?
Use the nearest dose not above the calculated dose, or a liquid.
References
- MHRA. Paracetamol: dose adjustment for adults with low body weight. Drug Safety Update.
- BNF. Paracetamol. bnf.nice.org.uk
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