Which eGFR equation?
NICE NG203 recommends CKD-EPI 2009 for creatinine, without the ethnicity adjustment. Most UK labs now report this.
When eGFR is unreliable
- Acute kidney injury
- Pregnancy
- Extremes of muscle mass, such as amputation or bodybuilding
- Within 12 hours of eating meat
Use CKD staging to add the ACR. For drug dosing, use creatinine clearance.
Frequently asked questions
Which eGFR equation does the NHS use?
CKD-EPI 2009, without adjustment for ethnicity (NICE NG203).
What is a normal eGFR?
90 or more is normal. Values of 60 to 89 are normal for many older adults without other kidney markers.
Should I use eGFR for DOAC dosing?
No. Use creatinine clearance (Cockcroft–Gault).
References
- Levey AS, Stevens LA, Schmid CH, et al. A new equation to estimate glomerular filtration rate. Ann Intern Med 2009;150(9):604–12.
- NICE. Chronic kidney disease: assessment and management. NG203. nice.org.uk/guidance/ng203
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