DAS28 Calculator for Rheumatoid Arthritis

Calculate DAS28-ESR or DAS28-CRP from joint counts, inflammatory marker and patient global health.

By Dr Amer Sheikh, GP Updated 17 October 2026 Clinical review pending

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DAS28 bands

DAS28	Disease activity
Below 2.6	Remission
2.6–3.2	Low activity
3.2–5.1	Moderate activity
Above 5.1	High activity

What you need

Tender joint count (0–28)
Swollen joint count (0–28)
ESR or CRP
Patient global health (0–100)

NICE NG100 advises a treat-to-target approach. Check biologic eligibility thresholds with rheumatology.

Frequently asked questions

What DAS28 score is remission?

Below 2.6.

Should I use DAS28-ESR or DAS28-CRP?

Either, but use the same one consistently for each patient.

What is high disease activity?

A DAS28 above 5.1.

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References

Prevoo ML, van ’t Hof MA, Kuper HH, et al. Modified disease activity scores that include twenty-eight-joint counts. Arthritis Rheum 1995;38(1):44–8.
NICE. Rheumatoid arthritis in adults: management. NG100. nice.org.uk/guidance/ng100

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